Common Questions and Answers about Doxycycline side effects sore throat doryx So do you think it's a herx or is it just a matter of the body getting use to the medication? Strep throat is an infection of the throat and tonsils caused by a Streptococcal bacteria. Typical symptoms are sore throat, chills, fever, and swollen lymph nodes in the neck. Sore throats that are caused by a viral infection usually get better on their own in two to seven days (). Yet some causes of a sore throat need to be treated. The sore throat went away and never came back, so I am assuming it did the trick. julies Post 2 I know that doxycycline is effective for treating strep in many cases, but my body must have built up some kind of resistance to it. We figured that he probably had a Doxycycline pill lodged in his esophagus that caused irritation. (We did not know it could be this terrible) Sadly, I think it IS an esophegal ulcer after reading all of these posts; but I am truly grateful to have found this thread. This is a bummer. I hope it doesn't take 8 weeks to heal. If anyone has over the counter advice, please share. I am very nervous. Can Doxycycline cause Sore Throat? Complete analysis from patient reviews and trusted online health resources, including first-hand experiences. Complete analysis from patient reviews and trusted online health resources, including first-hand experiences. Doctors give trusted answers on uses, effects, side-effects, and cautions: Dr. Sigari on can doxycycline cause your throat to be sore: Acid reflux can reach the back of the throat causing hoarseness, sore throat, and cough. Examining the area with a scope can see such irritation. Doxycycline can cure uncomplicated throat infection with a dose of 2 dose initial then 1 dose twice daily. So we were taught tetracyclines, like doxycycline, should NEVER be used for a sore throat. But a lot of what you learned turns out to be wrong. It it turned out there is a type of chlamydia called Chlamydia pneumoniae which causes a bad sore throat. Can Doxycycline Hyclate cause Sore Throat? Sore Throat is a known side effect of Doxycycline Hyclate. Complete analysis from patient reviews and trusted online health resources, including first-hand experiences.